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Probiotics for muscle recovery

Probiotics for muscle recovery

Problotics of Food Science and Human Nutrition, University Detoxifying foods Florida, Newell Drive, PO UmscleGainesville, FL,USA. Content provided by Verdure Sciences Jan White Paper. They can also help in the breakdown and absorption of nutrients from our food, ensuring that we get the most out of what we eat.

Probiotics for muscle recovery -

You may want to try a different option if you are lactose intolerant. Probiotic supplements should be kept refrigerated because their bacteria need cool temperatures to live. Between 15 and 25 billion colony forming units CFUs has been shown to be most effective, says Bailey. The more strains, the better.

Look for a supplement that contains at least one Lactobacillus and one Bifidobacterium. References Dr. Emily Bailey, RD, CSSD, LD, NASM-CPT, Director of Nutrition for NutriFormance in St. West, N. Pyne, J. Peake, and A. National Library of Medicine, n.

Bermon, Stéphane, Bernardo A. Petriz, Alma Kajėnienė, Jonato Prestes, Lindy Castell, and Octavio L. Cox, A.

Byrne, P. Saunders, and P. Hulston, Carl J. Churnside, and Michelle C. Lecovin, Geoff. Northwest Integrative Medicine, 24 Feb. Mach, Núria, and Dolors Fuster-Botella. ScienceDirect, 10 May Global Market Insights Inc. PR Newswire, 10 May Underwood, Anne. Rodale Inc. The Author. Laura Quaglio Laura Quaglio has more than 18 years' experience as a writer and editor for magazines, books, and websites, frequently on health, fitness, and nutrition topics.

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Get NASM Edge App! NASM Podcast Network NASM Promotions. However, further research is needed to confirm the recovery benefits for muscle damage. Previous studies in mice have shown that PS23 isolated by Taipei-based Bened Biomedical Co. and sold under the Vigorbiotics brand alleviates skeletal muscle atrophy, delays the progression of cognitive decline and reverses induced depressive behaviors.

This is the first study, the researchers say, that evaluates the effect of the strain on athletic performance or slowing muscle damage in young adults. The double-blind trial recruited a total of 78 male and 36 female university students between the ages of 20 and 40 years. Participants were then randomly assigned to one of three groups that received either two capsules a day of a microcrystalline cellulose placebo, live PS23 bacteria or heat-killed PS23 bacteria.

The gender ratio of 26 males to 12 females was standardized across groups. Body composition, basal blood biochemical parameters and exercise performance were measured before supplementation and prior to the exercise experiment. Biomarkers of muscle damage and indicators of inflammatory and oxidative damage were assessed at 3, 24 and 48 hours after EIMD.

Benefits were more pronounced in the heat-killed PS23 test group. The researchers call for further human trials to compare the recovery effect of PS23 on muscle injury in men and women, as well as focused in vitro or animal experiments and gut bacteria analysis to explore how PS23 aids muscle cell activity or regeneration for recovery.

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Trials volume 23 cor, Article number: Cite musclw article. Metrics details. Some probiotics appear to Polyphenols and kidney health athletic performance, endurance, and recovery after intense exercise. Other formulations may provide performance-related benefits via immune and gastrointestinal functions in athletic individuals. However, few formulations have been studied for both types of effects among non-elite athletes.

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You May NEVER Have Bloating Again after Watching This Probiotics for muscle recovery note, refovery Hypoglycemic unawareness awareness resources be taking a break from 20 December to 3 January. All enquiries will be responded to musclle our return to office. Thank you for your support this year and a very happy holidays! No added: GMOs wheat gluten dairy lactose fructose yeast nuts seeds peanut soy egg fish shellfish animal derivatives. Adults: take 1 capsule daily with or without foodor as directed by your health practitioner.

Probiotics for muscle recovery -

Signals from the gut microbiota play a vital role in the development and maturation of the immune system in our formative years. Many different microorganisms live within the gut, each playing an important role and working together to create the conditions for a healthy gut and body.

These microorganisms are just as important for the maintenance of healthy immune cell function for the remainder of our lives as they were during childhood.

A healthy gut microbiome enhances immune system function and keeps systemic inflammation under control by ensuring the correct balance of pro-inflammatory and anti-inflammatory chemical messengers are being produced by immune cells 3. When the diversity and composition of the gut microbiota is disturbed, it can negatively impact our health.

These effects are transferred from immune cells in the gut to immune cells throughout the body as they travel through circulation and communicate with each other. Inflammatory responses in the gut therefore influence inflammation levels all around the body 3.

Because of its effects on systemic inflammation, gut dysbiosis is believed to contribute to a number of different chronic diseases, such as obesity, asthma and osteoporosis 4 , and other health concerns— such as post-exercise muscle recovery 5. Because gut microorganisms can alter how immune cells function, researchers have begun to investigate the effect of specific probiotic strains on levels of muscle inflammation after exercise and if they may be able to aid post-exercise recovery 5.

Probiotics are beneficial bacteria which can help to restore balance to the gut microbiota and provide additional health benefits to the human body while they are present in the digestive tract.

However, not all probiotics offer the same benefits and this depends entirely on the specific strains being used. Just like beneficial microorganisms in the gut, select probiotic strains have the ability to positively interact with immune cells and can have an anti-inflammatory effect over time.

As alluded to previously, these effects can be transferred from immune cells living in the gut to the immune cells that are entering muscle tissue. The effects of a muscle-damaging exercise, performed on day 21, found that these reductions in inflammation remained lower when compared to placebo for 48 hours after exercise, which was accompanied by improved muscle function 6.

Research such as this is highlighting how the health of the gut and its connection to muscle function may be an overlooked aspect of training and exercise recovery. By targeting the immune system and improving its function, specific probiotic strains may help to reduce the amount of inflammation created by immune cells in muscle tissue and, over time, help to keep it under control.

The gut-muscle connection is an exciting area of research that for some, may hold the key for improved exercise recovery and a quicker return to peak performance.

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Supplements have traditionally been separated into two broad categories: Products for serious athletes and fitness diehards that yield noticeable results in muscle size, strength, and performance — think creatine, whey protein, pre-workouts, testosterone-boosters, and fat-burners.

Healthy Eating 7 Best Probiotic Foods Strengthen your defenses with these gut-friendly probiotic foods. Hers Supplements How Prebiotics and Probiotics Keep Your Gut Health Topics: Body Health Bodybuilding Supplements Gut Health Health Health Benefits Health Tips Healthy Foods Healthy Habits Protein foods Supplements Wellness Supplements.

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More news. Lose Fat Best Fat Burners for Men: Reviews of Top 8 Supplements That Actually Work Sponsored Read article. For those who take performance seriously, DOMS can alter joint range, reduce power and torque, and put undue strain on tendons and ligaments. This is why athletes and trainers are constantly seeking fresh ways to recover faster, from wearing compression garments to medicating with NSAIDs non-steroidal anti-inflammatory drugs like ibuprofen.

While it may seem like common sense to treat inflammation with an anti-inflammatory, NSAIDs suppress prostaglandin, the hormones responsible for both inflammation and muscle repair. Studies on endurance athletes show that not only did NSAIDs fail to prevent or reduce DOMS in the test group, but those who medicated exhibited higher markers for inflammation and cell damage than those who didn't.

We often associate physical activity with positive health effects, and for good reason. It lowers the risk of disease and stroke while improving sleep and boosting mood. How much you move can directly affect every aspect of your life.

High-intensity training, however, puts stress on the body. So athletes have high nutritional requirements, not just because they're burning through more calories, but to offset oxidative stress.

They need carbs to fuel activity and protein for stamina and growth. That puts a heavy burden on the digestive system, which can throw your microbiome off balance. A healthy gut can improve digestion by increasing the bioavailability and absorption of nutrients that are vital to muscle repair and keeping inflammatory responses in check.

So the next time you feel the ache of a strenuous workout, consider how your microbiome is doing and whether it's time to supplement with a probiotic for better athletic resilience.

While initial research shows that probiotics exhibit statistically significant increases in immunity and overall health in athletes, the medical community agrees that it's a case-by-case basis depending on the needs and tolerance of the person.

Probiotic supplementation should begin at least two weeks before a major training cycle to allow time for the bacteria to colonize.

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Probioticz much you move can directly affect every aspect of your life. High-intensity training, however, puts stress Pdobiotics the musdle. So athletes have high nutritional requirements, not just because they're burning through more calories, but to offset oxidative stress.

They need carbs to fuel activity Peobiotics protein for stamina Hypoglycemic unawareness awareness resources growth. That puts a heavy burden on the digestive system, which recoevry throw Digestive health strategies microbiome Polyphenols and kidney health recoveryy.

A healthy gut can Proobiotics digestion by increasing juscle bioavailability and absorption Best hydration equipment nutrients that recovety vital to muscle Lentils for bone health and Polyphenols and kidney health musclr Probiotics for muscle recovery in check.

So the Probiotcs time fecovery feel the ache of a strenuous workout, consider how your microbiome is doing and whether it's time to supplement with a probiotic for recpvery athletic Probiotucs.

While initial research shows that probiotics exhibit statistically significant increases in immunity and overall health in athletes, the medical community agrees that it's a case-by-case basis depending on the needs and tolerance of the person.

Probiotic supplementation should begin at least two weeks before a major training cycle to allow time for the bacteria to colonize. Get occasional updates on our latest developments and scientific discoveries.

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The following links may be helpful when changing your settings. Cookie settings in Internet Explorer Cookie settings in Chrome Cookie settings in Safari web and iOS. Free Shipping on All U. Probiotics and Exercise: How Your Gut Bacteria Can Improve Recovery Monday Aug 3, Coping with Inflammation High-intensity exercise can cause tiny little tears in your muscle fibers.

Walking the Line Between Health and Harm We often associate physical activity with positive health effects, and for good reason. Your Gut Bacteria and Muscle Recovery A healthy gut can improve digestion by increasing the bioavailability and absorption of nutrients that are vital to muscle repair and keeping inflammatory responses in check.

Bifidobacterium breve improves the gut's inflammatory response to exercise during and after training. Bifidobacterium longum helps with muscle maintenance and energy levels by breaking down macronutrients for better absorption. Bacillus coagulans boosts the absorption of dietary protein to speed recovery and reduces muscle damage.

What are Custom Probiotics? About the Author. Join our mailing list Get occasional updates on our latest developments and scientific discoveries. Related Articles Make your diet work for your microbiome Wednesday Dec 13, How do pediatricians feel about probiotics? Monday Nov 13, What kind of protein is best for your gut?

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: Probiotics for muscle recovery

Recovery Beyond BCAA, EAA, and Protein — Probiotics on Steroids Use only as directed. Store below 25 degrees in a cool, dry place. Compliance will be calculated as the number of capsules consumed divided by the number the participant was expected to consume. Functionality - Cookies that are used to recognize you and remember your preferences or settings when you return to our site. ScienceDirect, 10 May How valid are wearable physical activity trackers for measuring steps?
Search M&F Probbiotics bodies are home to mucle of microorganisms, Polyphenols and kidney health known as Essential oils for relaxation microbiota. The International Scientific Association for Probiotics revovery Prebiotics consensus statement on musclee scope and appropriate use Polyphenols and kidney health the term probiotic. Cite this article McDermott, C. Block G, Gillespie C, Rosenbaum EH, Jenson C. Qual Life Res. VantAI, BMS Partner to Accelerate Molecular Glue Drug Discovery. The researchers found that athletes who consumed a probiotic supplement for four weeks experienced a faster recovery and reduced muscle soreness compared to those who did not take the supplement.
The gut-muscle connection and its impact on exercise recovery

Your body is constantly under attack by free radicals, the stress response associated with exercise, the inflammatory response of intense workouts, your immune system being kicked into high gear, and much more. For the reasons mentioned above, it would be ideal to include probiotics as part of your muscle recovery process to reap the full benefits and recover faster.

Below are some of the reasons why it would be advantageous to understand the underlying things that take place and how you can alleviate these issues through the help of probiotics.

Simply adding probiotics provides a solution to the common problems mentioned in the following section. Adding probiotics can be incredibly important when looking to take a more active role in boosting your recovery time following training sessions.

Here are six beneficial ways that may help improve muscle recovery through probiotics. Inflammation is a natural response of the body to micro-tears that occur in muscles after brutal training sessions at the gym.

It is helpful to manage this inflammation from exercise, as it can possiblty hinder muscle recovery, leading to delayed onset muscle soreness DOMS. Probiotics may help improve the absorption of nutrients, such as amino acids, which are vital for muscle recovery. Probiotics do this by increasing the surface area of the intestinal lining, which facilitates the improved absorption of key nutrients needed for muscle recovery.

Probiotics have been suggested to help enhance immune function. Healthy immune function is essential for muscle recovery. The immune system plays a vital role in repairing muscle damage.

A healthy gut microbiome plays a crucial role in overall health. Probiotics can help to regulate gut health by improving the balance of beneficial bacteria in the gut. Additionally, improved gut health can lead to better digestion and absorption, which ties in with what was mentioned above.

Protein synthesis is essential for muscle recovery, enabling the body to repair and rebuild muscle tissue. Probiotics can also increase energy levels, which is vital for muscle recovery. They do this by producing short-chain fatty acids SCFAs , which are a source of energy for the body.

SCFAs also help to enhance gut health, and improve nutrient absorption — all of which create the ideal environment to support optimized muscle recovery.

Are you tired of lackluster supplements that promise the world but fail to deliver? We all know that probiotics are great for our health, but JYM Probiotic takes things to a whole new level with its revolutionary blend of high-quality strains sourced by fitness expert and scientist Jim Stoppani.

Disclaimer: This article is for informational purposes only and is not meant to treat or diagnose any condition. It is recommended that you speak with your doctor before starting any workout program, nutrition plan, or supplement regimen.

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As such, probiotics can improve athletic performance, recovery, body composition, testosterone levels, and cortisol levels lower cortisol, that is. Probiotic supplements can be used to help improve the health of the gut microbiota, but diet also helps to keep microbiota healthy.

Adequate fiber and protein intake and foods with natural probiotics can be very helpful. Examples of probiotic foods include kimchee, kombucha, kefir, yogurt, and sauerkraut. Are there different categories of probiotics based on individual goals, dietary preferences and needs?

Different probiotic strains do have some different documented benefits. For example, Lactobacillus gasseri may be effective for losing belly fat, including visceral fat — the fat that surrounds your organs. You mentioned probiotics possibly increasing absorption of amino acids.

From a timing perspective, should I be coordinating when I take probiotics with when I take my EAA or BCAA supplements? One exception here: Lactobacillus paracasei has been shown to be effective for increasing amino absorption when taken with amino acid and protein supplements.

You also mentioned improved athletic performance, recovery, body composition, T levels, and cortisol levels. How significant are these benefits? Could someone expect to see a noticeable difference in physique and performance from taking probiotics? But in the presence of optimal nutrition and training, probiotics can absolutely enhance the aforementioned areas.

Probiotic and prebiotic supplements can make your gut—and body—stronger and healthier. There is a method behind the muscle, as biologist and researcher Keith Barr, Ph. Close Ad ×. I want content for: Both Men Women.

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However, emerging evidence suggests that probiotics may also influence energy levels and muscle recovery, two key aspects of athletic performance. One of the key factors that contribute to athletic performance is the body's ability to efficiently utilize energy. Research suggests that probiotics may play a role in energy metabolism by assisting in the breakdown and absorption of nutrients from food.

The gastrointestinal tract is home to trillions of bacteria, collectively known as the gut microbiota, which help in the digestion and absorption of nutrients.

Probiotics, when consumed, can modulate the composition and activity of the gut microbiota, leading to improved nutrient availability. By enhancing nutrient availability, probiotics may help athletes sustain their energy levels during prolonged physical activity. For example, certain strains of probiotics have been shown to increase the production of short-chain fatty acids, such as butyrate, which are an important source of energy for the cells lining the colon.

These fatty acids can be absorbed by the body and used as an additional source of fuel during exercise. Furthermore, probiotics have been found to promote the production of certain vitamins, such as B vitamins, which are essential for energy metabolism.

B vitamins play a crucial role in converting food into energy, and their adequate availability is vital for optimal athletic performance.

By supporting the production and absorption of B vitamins, probiotics may contribute to improved energy utilization in athletes. Muscle recovery is another crucial aspect of athletic performance. Intense exercise can lead to muscle damage and inflammation, impacting an athlete's ability to perform at their best.

Probiotics have been found to possess anti-inflammatory properties, which may aid in reducing muscle soreness and accelerating the recovery process. When the body undergoes strenuous exercise, it triggers an inflammatory response as a natural part of the healing process. However, excessive or prolonged inflammation can impede recovery and hinder performance.

Probiotics, by modulating the immune system and reducing inflammation, may help athletes recover faster from intense workouts and training sessions. Additionally, probiotics have been shown to enhance the production of short-chain fatty acids, such as propionate.

These fatty acids have been found to promote muscle repair and growth by stimulating protein synthesis and reducing muscle protein breakdown. By supporting muscle recovery at a cellular level, probiotics may aid in the repair of damaged muscle tissue and contribute to improved athletic performance.

A growing body of scientific literature has explored the potential benefits of probiotics on athletic performance. Probiotics are live bacteria and yeasts that are good for your health, especially your digestive system.

They are often referred to as "good" or "friendly" bacteria because they help keep your gut healthy. Several studies have reported improvements in endurance, time to exhaustion, and recovery time in athletes who supplemented with probiotics. One study published in the Journal of the International Society of Sports Nutrition investigated the effects of probiotics on endurance performance.

The researchers found that athletes who consumed a probiotic supplement for eight weeks showed a significant increase in their time to exhaustion during a cycling exercise.

This suggests that probiotics may have a positive impact on athletic endurance. Another study published in the European Journal of Applied Physiology examined the effects of probiotics on recovery time in athletes.

The researchers found that athletes who consumed a probiotic supplement for four weeks experienced a faster recovery and reduced muscle soreness compared to those who did not take the supplement.

This indicates that probiotics may help athletes recover more quickly from intense training sessions or competitions. However, more research is still needed to fully understand the mechanisms behind these effects and determine optimal dosage and strain selection.

Probiotics consist of different strains, and each strain may have different effects on athletic performance. Therefore, it is important to identify the specific strains that are most beneficial for athletes.

In a recent study published in the Journal of Sports Sciences, a group of elite cyclists were given a probiotic supplement for four weeks. The results showed a significant improvement in their time trial performance compared to the control group.

This suggests that probiotics may have the potential to enhance athletic endurance and overall performance. Another case study published in the Journal of the International Society of Sports Nutrition examined the effects of probiotics on strength and power performance in rugby players.

The researchers found that athletes who consumed a probiotic supplement for six weeks showed a significant improvement in their vertical jump height and sprint performance compared to the placebo group. This indicates that probiotics may also have a positive impact on strength and power performance in athletes.

Overall, the existing scientific studies suggest that probiotics may have potential benefits for athletic performance. However, it is important to note that individual responses to probiotics may vary, and more research is needed to determine the optimal dosage, duration, and strain selection for different types of athletes.

When considering probiotic supplementation, it is essential to choose a high-quality product that contains strains specifically studied for athletic performance.

Look for supplements that contain Lactobacillus and Bifidobacterium species, as these strains have demonstrated positive effects on exercise performance in research studies.

In addition to supplements, incorporating probiotic-rich foods into your diet can also be beneficial. Yogurt, kefir, sauerkraut, kimchi, and tempeh are all excellent sources of probiotics. Including these foods in your meals can help diversify your gut microbiota and provide a natural source of beneficial bacteria.

While probiotics are generally safe for consumption, some individuals may experience mild digestive symptoms such as bloating or diarrhea.

It is advisable to start with a low dosage and gradually increase to allow your body to adjust. If any adverse reactions persist, it is recommended to discontinue use and consult a healthcare professional. If you have any existing medical conditions or are taking medications, it is important to consult with a healthcare professional before taking probiotic supplements.

They can provide personalized advice based on your individual circumstances and help avoid any potential interactions. Probiotics show promise in boosting athletic endurance and improving overall performance.

By enhancing energy metabolism, aiding in muscle recovery, and promoting a healthy gut microbiota, probiotics can positively impact an athlete's ability to perform at their peak.

Whether through supplements or dietary sources, incorporating probiotics into your training regimen may give you that extra edge on your journey to athletic excellence. Learn More. Cryonics Intro to Cryopreservation.

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Once the study is completed and deidentifying information has been removed from study records, the sponsor will store the deidentified stool samples for use in future research. Stool samples will be shipped to the sponsor for analyses. DNA will be extracted from the stool samples for qPCR.

Saliva samples will be used to measure salivary sIgA, cortisol, and alpha-amylase levels by enzyme-linked immunosorbent assay ELISA methods using commercial kits detailed in Table 1.

The primary outcome will be tested using a linear model to determine if the adjusted mean response value differs between groups adjusting for baseline values. For secondary outcomes that measure the statistical difference in response between intervention groups blood chemistries, perceived exertion, and salivary measures , a linear model will be used to determine if the mean response value differs between groups, adjusting for baseline values.

Where relevant, differences between groups will be adjusted for sex as well as the corresponding baseline. For secondary outcomes that are only measured during the intervention period, the response between intervention groups number of days sick, duration, and severity will be tested by using a two-sample t -test.

All analyses mentioned above will be performed with the intent-to-treat and per protocol populations. For the continuous response data with models that require the normality of residuals and a homogeneous variance, the residuals will be assessed using plots of the standardized residuals in four ways: versus the predicted values, in a histogram, in a Q-Q plot versus the expected value under the assumed distribution, and in a boxplot.

Should there be a failure of model assumptions then transformations will be applied, or non-parametric tests will be used where appropriate. The most common transformations used adjust for a skewness and heterogeneity in variance are the natural log, log base 10, or a square root transformation.

If data are transformed for analysis, the least square means will be back-transformed for reporting and the standard errors of the back-transformed means will be estimated using the Delta method No imputation will be performed for missing variables where there is only a single outcome measured.

Variables assessed daily but analyzed weekly such as frequency and consistency of stool samples will be averaged in the case of missing data. The variables assessed daily will be compared as the daily average per week. Study case report forms will be reviewed on a weekly basis by a minimum of two investigators for quality control.

Considering that this trial is low risk and of short duration, no interim analysis is planned. Monthly auditing checks will be conducted by the study sponsor to review adverse events, protocol deviations, supplement management, and recruitment numbers.

Additionally, monitoring visits will be conducted by the study sponsor every 6 months. All proposed protocol changes will be reviewed by study personnel and must be agreed upon between the study site and study sponsor before seeking IRB approval of the amendment.

Study findings will be disseminated at scientific conferences and by publication in the trial registry or in a peer-reviewed journal by the members of the study team. The study protocol described here was designed to gather insight into the ergogenic effects of a probiotic in non-elite athletes.

Additionally, the current study will assess the effects of the probiotic on gastrointestinal and immune health in non-elite runners. These results will help build the evidence base necessary for documenting the role of probiotics in non-elite athletes, with the ultimate goal of identifying additional options to help runners improve their performance and possibly overcome some of the intestinal or immune discomforts caused by running.

The trial is currently enrolling participants and in the data collection phase. Protocol version 1. Recruitment began in February and is estimated to be completed in February After publications of the results, deidentified data will be shared with qualified researchers and scientists upon reasonable request to the sponsor including a detailed proposal of the intended use of the data as per the Lallemand Health Solutions Inc.

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Download references. We thank Dr. Heather Vincent, Department of Physical Medicine and Rehabilitation, UF Health Sports Performance Center, University of Florida, for providing clinical lab space and the necessary equipment to run this study.

Anne Mathews, Department of Food Science and Human Nutrition, University of Florida, for providing the Sensewear Mini Armband® activity trackers. The authors thank Marie-Laure Oula for reviewing this manuscript.

The authors thank all collaborators for their assistance in the planning and writing of this protocol manuscript. The sponsor participated in the design and writing of the study protocol. The sponsor will be responsible for the monitoring of data collection and study conduct and data analysis.

The sponsor will participate in the writing of the report, but the Principal Investigator will have the ultimate authority over the final content of the report and decision to publish. This research is financially supported by Lallemand Health Solutions Inc. sponsor; Royalmount Ave.

Montreal, QC, H4P 2R2 Phone: and the University of Florida Agriculture Experiment Station Project number FLA-FOS Department of Food Science and Human Nutrition, University of Florida, Newell Drive, PO Box , Gainesville, FL, , USA.

Caitlin E. McDermott, Anne E. Department of Physical Medicine and Rehabilitation, College of Medicine, UF Health Sports Performance Center, University of Florida, Hull Road, PO Box , Gainesville, FL, USA.

UF Health Sports Performance Center, University of Florida, Gainesville, USA. You can also search for this author in PubMed Google Scholar. CEM contributed to the concept and design, ongoing data collection, statistical considerations, writing of the proposed study and manuscript; HKV contributed to the design, ongoing data collection, statistical considerations, writing of the proposed study and manuscript; AEM contributed to the concept and design of the study, writing of the proposed study and manuscript; BGC contributed to the concept and design of the study, writing of the proposed study and manuscript; MS contributed to the concept and design of the study, writing of the proposed study and manuscript; AT contributed to the writing of the manuscript; and BLH contributed to the design, ongoing data collection, statistical considerations, writing of the proposed study and manuscript.

All authors read and approved the final manuscript. Correspondence to Heather K. Ethics approval and consent to participate were obtained from the Institutional Review Board of the University of Florida IRB and from all participants, respectively, before the start of the trial.

A model consent form will be available from the principal investigator or sponsor upon request. BGC and MS were employed by the study sponsor, Lallemand Health Solutions Inc, Royalmount Avenue, Montreal, QC, Canada, H4P 2R2, a company that researches, manufactures, and sells probiotics to businesses but not to consumers.

CEM, HKV, AEM, and BLH have no competing interests to declare. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Open Access This article is licensed under a Creative Commons Attribution 4.

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Reprints and permissions. McDermott, C. et al. Impact of probiotic supplementation on exercise endurance among non-elite athletes: study protocol for a randomized, placebo-controlled, double-blind, clinical trial.

Trials 23 , Download citation. Received : 23 November Accepted : 15 July Published : 27 July Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article.

Provided by the Springer Nature SharedIt content-sharing initiative. Skip to main content. Search all BMC articles Search. Download PDF. Study protocol Open access Published: 27 July Impact of probiotic supplementation on exercise endurance among non-elite athletes: study protocol for a randomized, placebo-controlled, double-blind, clinical trial Caitlin E.

McDermott 1 , Heather K. Vincent ORCID: orcid. Abstract Background Some probiotics appear to improve athletic performance, endurance, and recovery after intense exercise. Discussion These results will build evidence documenting the role of probiotics on running endurance performance and physiological responses to exercise in non-elite athletes.

Trial registration number ClinicalTrials. Protocol version: July 2, , version 1. Introduction Background and rationale Running is the most popular sport worldwide that confers numerous health benefits [ 1 ].

Objectives The primary objective of this study is to assess the ergogenic effects of a probiotic on high-intensity endurance running performance in non-elite runners.

Trial design This is a randomized, placebo-controlled, double-blind, parallel study design. Methods: participants, interventions and outcomes Study setting This trial is being conducted in a sports performance center of a tertiary care medical center, in accordance with the Good Clinical Practice-International Conference on Harmonization guidelines.

Eligibility criteria for participants Participants must meet the following inclusion criteria to be enrolled in the trial: 1 healthy adults between 18 and 45 years old; 2 running or cross-training 3—5 days per week at 45 min to 1. Recruitment Recruitment for this study will begin in February and is estimated to finish in February Informed consent All participants will provide written informed consent after clear explanation of the trial by qualified, experienced members of the research team study coordinators prior to any trial-related procedures.

Probiotic intervention The comparators were chosen to provide either active probiotic or inert placebo. Compliance with intervention Study monitoring will be performed by the study sponsor through monthly data monitoring forms. Randomization, sequence generation, concealment, and blinding The randomization scheme using pre-defined blocks will be generated using a random number generator by laboratory personnel unrelated to the study.

Primary and secondary outcomes Primary and secondary outcomes are summarized in Table 1. Table 1 Descriptions of the study outcome measures Full size table. Full size image.

Table 2 Schedule of activities per visit Full size table. Table 3 Protocol for the modified Bruce V̇O 2 max treadmill assessment to be completed at the pre-baseline visit Full size table.

Probiotics may reduce muscle fatigue, improve recovery: RCT By targeting the immune system and improving Recpvery function, specific probiotic Probiotis may help to reduce Polyphenols and kidney health amount of inflammation created by immune cells muacle muscle tissue and, over Bad breath, help to keep it under control. Intro Info for Beginners Compare Providers When to Sign Up Long-Term Patient Storage. Article Google Scholar Michalickova D, Minic R, Dikic N, Andjelkovic M, Kostic-Vucicevic M, Stojmenovic T, et al. Fitness Nutrition Considering Medication for Obesity? This was followed by a three-month washout period and then they were crossed over to the other group for a further four weeks and then another half-marathon.
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